Innovative & Sustainable R&D | DEFT Chemicals - Manufacturing Xanthine Derivatives

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Research & Development

At DEFT, we don’t just innovate — we innovate responsibly. Our R&D mission is to build a better, cleaner, and healthier future through sustainable science.

At DEFT, innovation and responsibility go hand in hand. Our Research & Development division is committed to advancing science while preserving the environment, ensuring that every molecule we develop contributes to both human health and planetary well-being. We focus on creating cost-effective, high-quality Active Pharmaceutical Ingredients (APIs), intermediates, and specialty chemicals through sustainable and scalable technologies.

Our Focus Areas :

Novel and non-infringing route development
Process optimization for higher yield and purity
Reduction in raw material cost and environmental impact
Regulatory and market-driven development strategies
Green chemistry integration and E-factor reduction

Lab Scale Development

Our cutting-edge R&D lab provides the foundation for rapid and reliable innovation. Equipped with modern synthesis and screening tools, our team focuses on:

Route scouting and feasibility assessment
Atom economy and solvent recovery strategies
Impurity profiling and risk evaluation
Execution of development and validation batches

We prioritize minimal solvent usage, selection of safer reagents, and process designs that reduce by-products from the earliest stages.

Plant Scale Execution

Translating innovation from lab to large scale is a key strength at DEFT. Our robust plant-scale R&D support includes:

Pilot batch execution with eco-friendly process integration
Real-time monitoring and scale-up risk mitigation
Tech transfer with focus on cost, safety, and sustainability
Support for continuous improvement and regulatory documentation

We adopt Process Intensification techniques wherever feasible to minimize energy consumption and waste output at the manufacturing scale.

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Analytical Capabilities

Through dedicated R&D and Quality Control efforts, we uphold the highest standards of quality, sustainability, and regulatory compliance. Our key focus areas include analytical excellence, microbiology, and green chemistry initiatives, achieved through the following capabilities:

Green Analytical Method Development

Pilot batch execution with eco-friendly process integration
Real-time monitoring and scale-up risk mitigation
Tech transfer with focus on cost, safety, and sustainability
Support for continuous improvement and regulatory documentation

Comprehensive Material Testing

Raw materials and packaging materials
Real-time monitoring and scale-up risk mitigation
In-process samples and intermediates
Finished products

Stability Studies

Conducted as per ICH guidelines
Long-term and accelerated stability evaluations

Real-Time Monitoring

Detection and profiling of process-related impurities and degradation products
Enhanced process control and product safety

Advanced Analytical Instrumentation

HPLC, GC, UV-Vis, FTIR, Karl Fischer (KF), TGA, and more
Accurate, precise, and reliable analytical data

In-House Microbiology Laboratory

Microbial limit testing and sterility testing
Environmental monitoring for controlled manufacturing areas
Supports compliance with cGMP and regulatory guidelines

Sustainability & Green Chemistry

We are deeply committed to Green Chemistry Principles and Environmental Responsibility:

Use of renewable and recyclable raw materials where possible.
Minimized use of hazardous solvents and reagents.
Minimized use of water consumption.
Energy-efficient processes and batch-to-continuous conversions.
In-house solvent recovery and waste reduction systems.
EHS (Environment, Health & Safety)-driven R&D decision-making.

Our goal is to reduce the E-factor (waste-to-product ratio), minimize carbon footprint, and implement circular chemistry practices across all R&D activities.